#ReThinkNeuroimmunology Symposium 2024

September 25-27, 2024 at WashU Medicine

Symposium hosted by the BIG Center at WashU Medicine

A three day think tank exploring the biggest discoveries and breakthroughs in neuroimmunology, single cell genomics, immunology, and neuroscience.

September 25-27, 2024
WashU Medicine
St. Louis, MO

Organized by Jonathan Kipnis, WashU Medicine, and
Ido Amit, Weizmann Institute of Science

Registration now closed.


#ReThinkNeuroimmunology aims to define future directions of neuroimmunology, single cell genomics, immunology, and neuroscience, and the implementations of their discoveries in human health.

Neuroimmunology is today’s fastest growing biomedical sciences field targeting significant breakthroughs for treatment of neurodegenerative and psychiatric disorders.

Speakers

This unique meeting brings together the world’s leading neuroimmunology scientists, physicians, and industry leaders.

Ido Amit, Weizmann Institute
Ido Amit
Weizmann Institute
Azad Bonni
Roche
Azad Bonni
Roche
Anne Brunet, Stanford
Anne Brunet
Stanford University
Oleg Butovsky, Harvard
Oleg Butovsky
Harvard University
Menna Clatworthy, Univ of Cambridge
Menna Clatworthy
University of Cambridge
Karl Deisseroth, Stanford
Karl Deisseroth
Stanford University
Eran Elinav, Weizmann Institute
Eran Elinav
Weizmann Institute
Sten Linnarsson, Karolinska Institute
Sten Linnarsson
Karolinska Institute
Miriam Merad, Mount Sinai
Miriam Merad
Mount Sinai
Maiken Nedergaard, Stanford
Maiken Nedergaard
Rochester University
Hai Qi
Tsinghua University
Francisco Quintana, Harvard
Francisco Quintana
Harvard University
Aviv Regev, Genentech
Aviv Regev
Genentech
Margo Roberts
Lyell Immunopharma, Inc.
Michal Schwartz, Weizmann Institute
Michal Schwartz Weizmann Institute
Ziv Shulman
Weizmann Institute
Beth Stevens, Harvard
Beth Stevens
Harvard University

Program

Wednesday, September 25

8:00 – 9:30
Registration and breakfast

**8:15-9:30am: A SHUTTLE will run continuously from Chase Hotel to EPNEC auditorium.

9:30 – 10:00
Opening remarks

Jonathan Kipnis, WashU Medicine
Ido Amit, Weizmann Institute of Science

10:00 – 12:30
Session 1: Chaired by Jony Kipnis

Michal Schwartz, Weizmann Institute
Immunotherapy rejuvenates the brain-immune axis to boost protective autoimmunity to fight Alzheimer’s disease
10:00-10:30

Selected talk#1: Hachung Chung, Columbia University
10:30-10:45

Max Artyomov, WashU Medicine
Immune aging
10:45-11:15

Selected talk#2: Sandro Da Mesquita, Mayo Clinic
“Solving the functional links between meningeal lymphatic vessels and oligodendrocytes”
11:15-11:30

Karl Deisseroth, Stanford University – VIRTUAL
Light-gated membrane channels: Discovery and creation of diversity, principles from structure, and cellular access to biology
11:30-12:00

Azad Bonni, Roche
Challenges and Opportunities for Drug Development in Neurodegenerative Diseases
12:00-12:30

12:30 – 13:30
Lunch break and poster viewing

13:30 – 15:00
Session 2: Special Session

How can new models of collaboration between industry and academia disrupt the current landscape of Neuroimmunology

Session Title: “Bridging the Gap!” (13:30-14:15)

Moderator:
Skip Virgin, WashU Medicine

Panelists:
Margo Roberts, Lyell Immunopharma, Inc.
Nikhil Wagle, Genentech
Frank Gentile, Casma Therapeutics
Vineeta Agarwala, Andreessen Horowitz

Q&A from audience: (14:15-15:00)

15:00 – 15:45
Coffee break and poster viewing

*Vote for best poster!

15:45-18:30
Session 3: Chaired by Rejane Rua

Adam Kepecs, WashU Medicine
From Cytokines to Circuits: Neural mechanisms of cachexia-induced depression
15:45-16:15

Hai Qi, Tsinghua University
Anticipatory immune posturing via the brain-spleen axis
16:15-16:45

Selected Talk 3: Adrienne Antonson, Univ of Illinois Urbana-Champaign
Compromised placental and fetal brain barriers during maternal viral infection
16:45-17:00

Anne Brunet, Stanford University
Targeting immune cells and inflammation in the old brain
17:00-17:30

Eynav Klechevsky, WashU Medicine
17:30-18:00

Ido Amit, Weizmann Institute
The power of ONE: Immunology in the age of spatial and single cell genomics
18:00-18:30

19:00-20:30

Reception at Neuroscience Research Building (NRB)

4370 Duncan Ave. St. Louis, MO. 63110

*The NRB is a 10 min walk in the link from EPNEC. There is also a continuously running shuttle from EPNEC to the NRB/Cortex.

20:30-22:00

Urban Chestnut Brewery in Tower Grove

4465 Manchester Ave., St. Louis, MO. 63110
*Must have RSVP’ed to attend this event. Will be noted on your badge.

*20:00/8pm: A BUS will begin transporting guests from the NRB to UCBC in Tower Grove. Will make multiple trips.

*21:45/9:45pm: A BUS will begin transporting guests from UCBC in Tower Grove, to Chase Hotel and DoubleTree Hotel. Will make multiple trips until 10:30pm.

Thursday, September 26

8:00 – 9:00
Registration and breakfast

**8-9am: A SHUTTLE will run continuously from Chase Hotel to EPNEC auditorium.

9:00 – 12:00
Session 4: Chaired by Anna Molofsky

Maiken Nedergaard, Rochester University
The Glymphatic System
9:00-9:30

Beth Stevens, Harvard University
Diurnal Regulation of the Brain Innate Immune Compartment Across the Lifespan
9:30-10:00

Oleg Butovsky, Harvard University
APOE4-Dependent Immune Checkpoints Control Neutrophil-Microglia Interactions Driving Cognitive Impairment in Alzheimer’s Disease
10:00-10:30

Li Huei Tsai, MIT
10:30-11:00

Ruslan Medzhitov, Yale University
Why Neuroimmune Interactions?
11:30-12:00

12:00 – 13:30
Lunch break and poster viewing

*Vote for best poster!

13:30 – 15:15
Session 5: Chaired by Marco Colonna

Francisco Quintana, Harvard University
13:30-14:00

Selected Talk 4: Alejandra Mendoza, Scripps Research
14:00-14:15

Dori Schafer, UMass
Mechanisms driving microglia dysfunction during neurodegeneration
14:15-14:45

Gwendalyn Randolph, WashU Medicine
Trafficking and function of HDL particles enriched in apoA1 or apoE
14:45-15:15

15:15 – 16:00
Coffee break and poster viewing

16:00 – 18:15
Session 6: Chaired by Beth Stevens

Anna Molofsky, UCSF
Cytokine regulation of brain development
16:00-16:30

Marco Colonna, WashU Medicine
16:30-17:00

Selected Talk 5: Danyang He, Westlake University
17:00-17:15

Rejane Rua, CIML
Brain borders control neurodevelopment and neuroinflammation
17:15-17:45

Jonathan Kipnis, WashU Medicine
New therapeutic approaches for brain disorders
17:45-18:15

18:45 – 20:30
Free time

20:30 – 24:00/Midnight

City Museum/Dance Party

750 North 16th St., St. Louis, MO. 63103
*Must have RSVP’ed to attend this event. Will be noted on your badge.

*20:00 (8pm): A BUS will begin transporting guests from DoubleTree Hotel to the City Museum.
*20:30 (8:30pm): A BUS will make another run from Doubletree to the City Museum.
*23:30 (11:30pm): TWO BUSES will begin returning guests to Chase Hotel and Doubletree.
*24:00 (Midnight): TWO BUSES will make another run from the City Museum to Chase Hotel and Doubletree.

*PARKING FOR CITY MUSEUM: The Serpent Lot is $15, pay upon entry.
FREE PARKING is available on the street.

Friday, September 27

8:30 – 9:30
Registration and breakfast

**8-9:30am: A SHUTTLE will run continuously from Chase Hotel to EPNEC auditorium.

9:30-11:30
Session 7: Chaired by Dori Schafer

Menna Clatworthy, University of Cambridge, VIRTUAL
9:30-10:00

Selected Talk 6: Hussein Sultan, WashU Medicine
10:00-10:15

Philip De Jager, Columbia University
Modeling glial states: towards a shared taxonomy of microglia uncovers
10:15-10:45

Selected Talk 7: Tyler Miller, Case Western Reserve Univ School of Med
Understanding and targeting immunomodulatory myeloid cells in glioma
10:45-11:00

Kodi Ravichandran, WashU Medicine
Circadian control of efferocytosis
11:00-11:30

11:30 – 13:00
Lunch break and poster viewing

13:00 – 15:00
Session 8: Chaired by Ido Amit

Ziv Shulman, Weizmann Institute
Antibody-mediated immune responses in the upper airways
13:00-13:30

Selected Talk 8: Tristan Li, WashU Medicine
Microglial plasticity governed by state-specific enhancer landscapes
13:30-13:45

Sten Linnarson, Karolinska Institute
Futile wound healing drives ’mesenchymal’ cell states in human glioblastoma
13:45-14:15

Selected Talk 9: Jessica Crowley, Icahn School of Medicine, Mount Sinai
14:15-14:30

David Holtzman, WashU Medicine
Role of APOE, glial lipid metabolism, and the immune response in amyloid and tau-linked neurodegeneration
14:30-15:00

**BEST POSTER WINNERS to be announced**

Poster session

Poster presenters were chosen on August 15th to showcase their work and/or deliver a short talk to an international audience as part of the conference program.

****POSTER PRESENTERS: Bulletin Board list & presentation day listed HERE. ****

  • The top 5 posters will receive free registration (up to $360).
  • POSTER VOTING: One submission per attendee. Vote for up to 3 posters by 1pmCT on Friday Sept27th. Voting link is HERE! Opens at 9am on Sept25th and closes at 1pm on Sept27th!
  • Information is HERE for poster sizes, printing options, and poster delivery info.
  • PLEASE NOTE: You must have registered for the symposium to present a poster.
  • BADGES MUST BE CLEARLY DISPLAYED at all times during the symposium and social events!!

    Registration is now CLOSED.

Please contact Events Manager Tracy Duckett with questions duckettt@wustl.edu.

Location

Eric P. Newman Education Center (EPNEC)
Washington University Medical Campus
Open map »

Lodging

DoubleTree by Hilton (just steps from EPNEC Auditorium)
4550 Forest Park Ave.
St. Louis, Missouri 63108 USA | map
Reserve now: RTN2024 Group Rate/DoubleTree
*Complimentary Parking ($15/day value)
*Their 3rd floor connects to EPNEC
Auditorium

The Chase Park Plaza Royal Sonesta St. Louis (a 10 min walk from EPNEC Auditorium)
212 Kingshighway Blvd.
St. Louis, MO 63108 USA | map
Reserve now: RTN2024 Group Rate/Chase

Social Events & Shuttle Info

Social Events Schedule

Event day/timeTransportation provided to/from social event
**SPEAKERS or PRIVATE INVITATION ONLY**

Tues, Sept 24 @ 18:30: 

Speaker Reception
Four Seasons Hotel
999 N. 2nd St. Louis, MO 63102

**Outdoor event on rooftop terrace, please dress accordingly**
**SPEAKERS or PRIVATE INVITATION ONLY**

1) 5:45pm/17:45:  Shuttle pickup from Chase Hotel (Lindell Ave. side near movie theater marquis).
2) 5:55pm/17:55: Shuttle pickup from Doubletree Hotel.
3) 10pm/22:00: Shuttle returning guests to both hotels at the end of the evening. 

*Free valet or garage parking at Four Seasons if you mention the WashU event.
Wed, Sept 25 @ 19:00-20:30pm:

Cocktail hour at the Neuroscience Research Bldg, 4370 Duncan Ave. St. Louis, MO. 63110
Guests will walk the link to the NRB from EPNEC Auditorium.
***You must have previously RSVP’ed for this event in order to attend***

Wed, Sept 25 @ 20:00-22:00: 

Urban Chestnut Brewery in Tower Grove
4465 Manchester Ave., St. Louis, MO 63110
1) 8pm/20:00: 1st bus departing NRB for UCBC.
2) 8:30pm/20:30: 2nd bus departing NRB for UCBC.  (Or you may arrange an Uber back to hotel).
3) 9:45pm/21:45: RETURN TRIP to DoubleTree & Chase.
4)10pm/22:00:  RETURN TRIP to DoubleTree & Chase
**SPEAKERS or PRIVATE INVITATION ONLY**

Thurs, Sept 26 @ 18:45-20:45pm: 

Speaker dinner at Vicia
4260 Forest Park Ave. Ave., St. Louis, MO. 63108
**SPEAKERS ONLY**

18:40:  Bus departing EPNEC for Vicia.  (or, a 15 min walk).
***You must have previously RSVP’ed for this event in order to attend***

Thurs, Sept 26 @ 20:30-midnight: 

City Museum/Dance Party
750 North 16th St. St. Louis, MO. 63103
1) 20:00 & 20:30: Bus departing DoubleTree Forest Park, to City Museum. **You will need to Uber if not departing from this location.
2) 20:45: **SPEAKERS**: Bus departing Vicia for Chase then City Museum.
3) 23:15: RETURN TRIP – Bus departing City Museum to Chase, then Doubletree.
4) Midnight:  RETURN TRIP -Bus departing City Museum to Chase, then Doubletree.

*PARKING FOR CITY MUSEUM: The Serpent Lot is $15, pay upon entry. FREE PARKING is available on the street.
Daily SHUTTLE from Chase to EPNEC auditorium
Wed, Sept 25
8:15am – 9:30am
Shuttle running continuously from Chase Hotel to EPNEC auditorium. 
On the Lindell Ave side, near the movie theater marquis.
Thurs, Sept 26
8am – 9am
Fri, Sept 27
8:15am – 9:30am

Sponsors

Diamond Level
Brain Immunology and Glia (BIG) Center
NeuroScience Innovation Foundation
gold Level
silver Level
Eisai Global
Cure Alzheimer’s Fund
Genentech Roche
bronze level
Corsalex
Other
How to sponsor this event

The BIG Center at Washington University in St. Louis is honored to serve as the title sponsor of this meeting, and we are asking you to join us in supporting this incredibly important collaboration of scientists, clinicians, industry leaders and world experts in neuroimmunology. Sponsors will be well publicized at our symposium by having their logo on our meeting website. In addition, exhibitor booths will be available to display your printed materials.

Sponsorship tiers:

  • Diamond Level = $50k
  • Gold Level = $25k
  • Silver level = $15k
  • Bronze level = <$10k

Please contact our Events Manager Tracy Duckett for more information at duckettt@wustl.edu.

Organizers

BIG Center at WashU Medicine

WashU Medicine is pushing the bounds of medicine and improving health in our community and around the world. Studying the complex relationships between the brain and the immune system, the Brain Immunology & Glia (BIG) Center aims to inform and develop new treatments for neurological diseases.

Weizmann Institute of Science

The Weizmann Institute has a long history of investigation and discovery rooted in a mission of advancing science for the benefit of humanity. In parallel, it educates a substantial proportion of Israel’s scientific leadership and advances science literacy in schools and among the public.

Contact the Conference Coordinator

Tracy Duckett
BIG Center Administrative Assistant
314-273-2288
duckettt@wustl.edu

If you are a conference participant with special accessibility needs, please contact us and we will make all necessary arrangements for you.