Associate Professor, Department of Psychiatry
Research Interests
Oxysterols are hydroxylated cholesterols, which influence a wide variety of cellular pathways including endolysosomal trafficking, cholesterol biosynthesis and cell surface and nuclear receptor signaling among others. These intracellular effects manifest as major regulatory steps in lipid homeostasis, inflammatory signaling, neuromodulation and cell migration. We are interested in understanding how oxysterols influence neuroinflammation, synaptic dysfunction and neurodegeneration in Alzheimer’s disease.
Professional Education
- BSc: Bangalore University, Bengaluru, India, 1989
- PhD: Jawaharlal Nehru University, New Delhi, India, 1997
- MSc: Madurai Kamaraj University, Madurai, India, 1991
Affiliations
- Assistant Professor of Psychiatry Member
- Hope Center for Neurological Disorders Member
- Taylor Family Insititute for Innovvative Psychiatric Research
Cashikar Lab
Oxysterols are hydroxylated cholesterols, which influence a wide variety of cellular pathways including endolysosomal trafficking, cholesterol biosynthesis and cell surface and nuclear receptor signaling among others. These intracellular effects manifest as major regulatory steps in lipid homeostasis, inflammatory signaling, neuromodulation and cell migration. We are interested in understanding how oxysterols influence neuroinflammation, synaptic dysfunction and neurodegeneration in Alzheimer’s disease.