Associate Professor of Neurology
Research Interests
We are focused on identifying and understanding molecular mechanisms of neurodegeneration in the mammalian brain. We study the circadian clock system and how it regulates glia function, neuroinflammation, protein aggregation, and neurodegeneration.
Areas of current interest include:
- Circadian clocks in Alzheimer’s Disease pathogenesis
- Regulation of glial function and neuroinflammation by the circadian clock
- Interplay between aging, the circadian clock, and neurodegeneration
- The role of glial cells in neurodegenerative diseases
- Novel therapeutic targets for Alzheimer’s Disease
Professional Education
- BSc: 1999 Biological Psychology, College of William and Mary, Williamsburg, Virginia
- PhD: 2005 Pharmacology, Vanderbilt University, Nashville, Tennessee
- MD: 2007 Vanderbilt University, Nashville, Tennessee
- Residency: 2011 Neurology, University of Pennsylvania, Philadelphia, Pennsylvania
- Fellowship: 2012 Alzheimer’s Disease Research, Washington University School of Medicine, St. Louis, Missouri
Affiliations
- Neurology
- Adult Neurology
- Hope Center for Neurological Disorders
- Biology & Biomedical Sciences
- Cure Alzheimer’s Fund
Musiek Lab
The Musiek lab examines how the circadian clock influences neuroinflammation, glial activation and function, protein aggregation, and neurodegeneration in mouse models of Alzheimer’s Disease and other degenerative conditions.